BARHL2

Entrez Summary: N/A
UniProt Summary: Potential regulator of neural basic helix-loop-helix genes. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cell fate determination
regulation of axon extension
regulation of extent of cell growth
neuron migration
positive regulation of translation
positive regulation of cellular amide metabolic process
regulation of cell size
regulation of axonogenesis
cell fate commitment
regulation of cell morphogenesis involved in differentiation
RNA polymerase II regulatory region sequence-specific DNA binding
regulation of developmental growth
regulation of translation
regulation of cellular component size
regulation of cellular amide metabolic process
regulation of cell growth
DNA-binding transcription activator activity, RNA polymerase II-specific
regulation of cell morphogenesis
regulation of neuron projection development
regulation of anatomical structure size
posttranscriptional regulation of gene expression
regulation of neuron differentiation
regulation of growth
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
cell migration
neuron differentiation
regulation of anatomical structure morphogenesis
localization of cell
cell motility
positive regulation of transcription by RNA polymerase II
locomotion
generation of neurons
positive regulation of transcription, DNA-templated
movement of cell or subcellular component
DNA-binding transcription factor activity, RNA polymerase II-specific
positive regulation of cellular protein metabolic process