BOD1

Entrez Summary: N/A
UniProt Summary: Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles. {ECO:0000269|PubMed:17938248}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

mitotic sister chromatid biorientation
mitotic sister chromatid cohesion, centromeric
sister chromatid biorientation
centromeric sister chromatid cohesion
condensed chromosome outer kinetochore
attachment of mitotic spindle microtubules to kinetochore
mitotic sister chromatid cohesion
protein localization to chromosome, centromeric region
attachment of spindle microtubules to kinetochore
protein phosphatase 2A binding
protein phosphatase inhibitor activity
spindle microtubule
mitotic metaphase plate congression
sister chromatid cohesion
metaphase plate congression
negative regulation of phosphoprotein phosphatase activity
protein localization to chromosome
negative regulation of protein dephosphorylation
establishment of chromosome localization
chromosome localization
negative regulation of phosphatase activity
mitotic sister chromatid segregation
negative regulation of dephosphorylation
regulation of phosphoprotein phosphatase activity
spindle pole
regulation of protein dephosphorylation
sister chromatid segregation
mitotic nuclear division
regulation of phosphatase activity
regulation of dephosphorylation
nuclear chromosome segregation
chromosome segregation
nuclear division
organelle fission
establishment of organelle localization
negative regulation of hydrolase activity
centrosome
cell division
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process