BRS3

Entrez Summary: N/A
UniProt Summary: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
Lead acetate 2000μM R08 exp498 no dilution day6	-1.94
Quinacrine 2.5μM R03 exp146	1.8

bombesin receptor signaling pathway
bombesin receptor activity
adult feeding behavior
feeding behavior
glucose metabolic process
adult behavior
hexose metabolic process
regulation of blood pressure
monosaccharide metabolic process
neuron projection
neuronal cell body
blood circulation
circulatory system process
carbohydrate metabolic process
behavior
G protein-coupled receptor activity
G protein-coupled receptor signaling pathway
integral component of plasma membrane
small molecule metabolic process
system process