BSPRY

Entrez Summary: N/A
UniProt Summary: May regulate epithelial calcium transport by inhibiting TRPV5 activity. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

zf-B box
SPRY

cell leading edge
cellular response to leukemia inhibitory factor
response to leukemia inhibitory factor
calcium ion transport
divalent metal ion transport
divalent inorganic cation transport
metal ion transport
perinuclear region of cytoplasm
cation transport
zinc ion binding
cellular response to cytokine stimulus
response to cytokine
ion transport
membrane