BTLA

Entrez Summary: N/A
UniProt Summary: Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. {ECO:0000269|PubMed:12796776}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Campthothecin 0.001μM R06 exp270	-1.77
Actinomycin-D 0.01μM R00 exp4	2

T cell costimulation
lymphocyte costimulation
positive regulation of T cell activation
signaling receptor activity
positive regulation of leukocyte cell-cell adhesion
positive regulation of cell-cell adhesion
regulation of leukocyte cell-cell adhesion
regulation of T cell activation
positive regulation of lymphocyte activation
regulation of cell-cell adhesion
positive regulation of leukocyte activation
positive regulation of cell adhesion
positive regulation of cell activation
immune response-regulating cell surface receptor signaling pathway
regulation of lymphocyte activation
immune response-regulating signaling pathway
regulation of leukocyte activation
adaptive immune response
regulation of cell activation
regulation of cell adhesion
positive regulation of immune system process
regulation of immune response
integral component of plasma membrane
regulation of immune system process
immune response