C1S

Gene Information
  • Official Symbol: C1S
  • Official Name: complement C1s
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 716
  • UniProt: P09871
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9606
  • Expression level (log2 read counts): 2.8

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1