C9orf156
Gene Information
- Official Symbol: TRMO
- Official Name: tRNA methyltransferase O
- Aliases and Previous Symbols: N/A
- Entrez ID: 51531
- UniProt: Q9BU70
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability. May bind to tRNA (By similarity). {ECO:0000250|UniProtKB:P28634, ECO:0000269|PubMed:25063302}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15786
- Expression level (log2 read counts): 4.15