CCDC103

Entrez Summary: This gene encodes a protein that contains a coiled-coil domain. [provided by RefSeq, Apr 2012].
UniProt Summary: Dynein-attachment factor required for cilia motility. {ECO:0000269|PubMed:22581229}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Hinokiflavone 12μM R08 exp487	-1.78
Resveratrol 16μM R03 exp147	1.7

determination of digestive tract left/right asymmetry
outer dynein arm
epithelial cilium movement involved in determination of left/right asymmetry
inner dynein arm assembly
outer dynein arm assembly
epithelial cilium movement involved in extracellular fluid movement
extracellular transport
axonemal dynein complex assembly
cilium movement
heart looping
axoneme assembly
embryonic heart tube morphogenesis
determination of heart left/right asymmetry
embryonic heart tube development
microtubule bundle formation
motile cilium
axoneme
determination of left/right symmetry
determination of bilateral symmetry
specification of symmetry
digestive tract development
digestive system development
microtubule-based transport
heart morphogenesis
microtubule-based movement
embryonic organ morphogenesis
epithelial tube morphogenesis
cilium assembly
cilium organization
morphogenesis of an epithelium
embryonic organ development
pattern specification process
plasma membrane bounded cell projection assembly
cell projection assembly
microtubule cytoskeleton organization
heart development
tissue morphogenesis
embryonic morphogenesis
tube morphogenesis
microtubule-based process