CEACAM8

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
GSK-J4 1.5μM R08 exp441	1.95
GSK2606414 1μM R05 exp236	1.96

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
azurophil granule membrane
tertiary granule membrane
specific granule membrane
anchored component of membrane
cell-cell adhesion via plasma-membrane adhesion molecules
leukocyte migration
neutrophil degranulation
protein heterodimerization activity
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
cell-cell adhesion
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
cell surface
leukocyte activation involved in immune response
cell activation involved in immune response
regulated exocytosis
leukocyte mediated immunity
exocytosis
leukocyte activation
cell adhesion
biological adhesion
cell migration
secretion by cell
export from cell
cell activation
localization of cell
cell motility
immune effector process
secretion
locomotion
movement of cell or subcellular component
extracellular space
immune response
vesicle-mediated transport