CHI3L2

Entrez Summary: N/A
UniProt Summary: Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity. {ECO:0000269|PubMed:22742450}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Benzoate 10000μM R08 exp455	-1.75
Ibrutinib 1μM R07 exp372	1.72

chitin metabolic process
chitin catabolic process
chitinase activity
chitin binding
glucosamine-containing compound catabolic process
amino sugar catabolic process
glucosamine-containing compound metabolic process
amino sugar metabolic process
aminoglycan catabolic process
drug catabolic process
aminoglycan metabolic process
carbohydrate binding
carbohydrate derivative catabolic process
carbohydrate metabolic process
drug metabolic process
carbohydrate derivative metabolic process
macromolecule catabolic process
organonitrogen compound catabolic process
extracellular space
organic substance catabolic process
cellular catabolic process
extracellular region