CRIP1

Entrez Summary: N/A
UniProt Summary: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Phenformin 20μM R03 exp143	1.77
L-74142 5μM R03 exp131	1.95

prostate gland stromal morphogenesis
cellular response to UV-B
AT DNA binding
response to UV-B
DNA binding, bending
prostate gland morphogenesis
prostate gland development
peptide binding
response to zinc ion
intrinsic apoptotic signaling pathway in response to DNA damage
cellular response to UV
gland morphogenesis
cellular response to light stimulus
cellular response to antibiotic
response to UV
intrinsic apoptotic signaling pathway
cellular response to radiation
connective tissue development
apoptotic signaling pathway
response to antibiotic
response to light stimulus
cellular response to environmental stimulus
cellular response to abiotic stimulus
urogenital system development
response to metal ion
gland development
reproductive structure development
reproductive system development
response to radiation
heart development
response to inorganic substance
cell population proliferation
developmental process involved in reproduction
cellular response to DNA damage stimulus
zinc ion binding
circulatory system development
apoptotic process
animal organ morphogenesis
programmed cell death
cell death