CRYL1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Isonicotinamide 500μM R03 exp129	1.82
Vinblastine 0.2μM R03 exp108	1.82
Nicotinamide Riboside 100μM R03 exp139	1.9

3HCDH
3HCDH N

L-gulonate 3-dehydrogenase activity
glucuronate catabolic process
xylulose 5-phosphate metabolic process
xylulose 5-phosphate biosynthetic process
glucuronate catabolic process to xylulose 5-phosphate
3-hydroxyacyl-CoA dehydrogenase activity
NAD+ binding
uronic acid metabolic process
glucuronate metabolic process
monosaccharide catabolic process
monocarboxylic acid catabolic process
carbohydrate catabolic process
monosaccharide metabolic process
organic acid catabolic process
carboxylic acid catabolic process
fatty acid metabolic process
small molecule catabolic process
carbohydrate metabolic process
monocarboxylic acid metabolic process
organophosphate biosynthetic process
carbohydrate derivative biosynthetic process
protein homodimerization activity
organophosphate metabolic process
carboxylic acid metabolic process
cellular lipid metabolic process
oxidation-reduction process
oxoacid metabolic process
organic acid metabolic process
carbohydrate derivative metabolic process
lipid metabolic process
small molecule metabolic process
organic substance catabolic process
cellular catabolic process