CYB5D2

Entrez Summary: N/A
UniProt Summary: Heme-binding protein which promotes neuronal but not astrocyte differentiation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Metformin 40μM R03 exp132	-1.71
UM0125461 0.74μM R02 exp84	1.97

heme binding
positive regulation of neuron differentiation
positive regulation of neurogenesis
positive regulation of nervous system development
positive regulation of cell development
regulation of neuron differentiation
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation
positive regulation of developmental process
generation of neurons
neurogenesis
positive regulation of multicellular organismal process
regulation of cell differentiation
extracellular region