DEFB125

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rifampicin 30μM R08 exp430	-1.96
Milciclib 2μM R08 exp502	-1.85
Chloroquine 32μM R08 exp470	-1.78
BH1 1μM R04 exp169	1.72
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	2.04

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

defense response to bacterium
response to bacterium
innate immune response
defense response to other organism
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
immune response
extracellular region