DENND5B

Gene Information
  • Official Symbol: DENND5B
  • Official Name: DENN domain containing 5B
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 160518
  • UniProt: Q6ZUT9
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20937701}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7261
  • Expression level (log2 read counts): 5.42

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1