DEPDC1B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
SB202190 10μM R03 exp148	-1.71
proTAME 5μM R04 exp187	1.78

DEP
RhoGAP

positive regulation of Wnt signaling pathway
GTPase activator activity
regulation of small GTPase mediated signal transduction
regulation of Wnt signaling pathway
positive regulation of GTPase activity
regulation of GTPase activity
positive regulation of hydrolase activity
cell migration
localization of cell
cell motility
regulation of hydrolase activity
locomotion
positive regulation of catalytic activity
movement of cell or subcellular component
positive regulation of signal transduction
intracellular signal transduction
positive regulation of molecular function
positive regulation of cell communication
positive regulation of signaling
regulation of intracellular signal transduction