DEXI

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK2606414 1μM R05 exp236	-2.5
BAY-598 4μM R05 exp220	-2.22
Deguelin 0.15μM R05 exp209	-2.16
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	-2.01
Betulinic acid 10 to 15μM on day4 R05 exp222	-1.95
LLY-284 2.6μM R06 exp291	-1.85
HMS-I2 10μM R06 exp288	-1.71
Dorsomorphin 5μM R07 exp357	2

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution