DPCD

Entrez Summary: This gene in mouse encodes a protein that may be involved in the generation and maintenance of ciliated cells. In mouse, expression of this gene increases during ciliated cell differentiation, and disruption of this gene has been linked to primary ciliary dyskinesia. [provided by RefSeq, Jul 2016].
UniProt Summary: May play a role in the formation or function of ciliated cells. {ECO:0000269|PubMed:14630615}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

third ventricle development
lateral ventricle development
left/right pattern formation
ventricular system development
epithelial cilium movement involved in extracellular fluid movement
extracellular transport
cilium movement
flagellated sperm motility
sperm motility
cilium-dependent cell motility
cilium or flagellum-dependent cell motility
determination of left/right symmetry
determination of bilateral symmetry
specification of symmetry
microtubule-based transport
telencephalon development
microtubule-based movement
regionalization
forebrain development
pattern specification process
spermatogenesis
male gamete generation
microtubule-based process
gamete generation
brain development
head development
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
central nervous system development
multi-organism reproductive process
cell motility
localization of cell
locomotion
reproductive process
reproduction
movement of cell or subcellular component
extracellular region