EDIL3

Entrez Summary: N/A
UniProt Summary: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
R-DABN 8μM R03 exp111	-1.74
MK-1775 0.32μM R02 exp75	2.23

EGF
F5 F8 type C

extracellular vesicle
positive regulation of cell-substrate adhesion
integrin binding
extracellular matrix structural constituent
regulation of cell-substrate adhesion
collagen-containing extracellular matrix
positive regulation of cell adhesion
regulation of cell adhesion
calcium ion binding
cell adhesion
biological adhesion