EIF2A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

eukaryotic translation initiation factor 2 complex
SREBP signaling pathway
cellular response to sterol depletion
response to sterol depletion
ER-nucleus signaling pathway
cytosolic small ribosomal subunit
response to amino acid starvation
translation initiation factor activity
ribosome binding
tRNA binding
ribosome assembly
blood microparticle
translational initiation
response to starvation
ribonucleoprotein complex assembly
ribonucleoprotein complex subunit organization
ribosome biogenesis
cadherin binding
regulation of translation
translation
regulation of cellular amide metabolic process
peptide biosynthetic process
ribonucleoprotein complex biogenesis
response to nutrient levels
posttranscriptional regulation of gene expression
amide biosynthetic process
peptide metabolic process
response to extracellular stimulus
organelle assembly
cellular amide metabolic process
cellular protein-containing complex assembly
protein phosphorylation
positive regulation of transcription by RNA polymerase II
phosphorylation
organonitrogen compound biosynthetic process
positive regulation of transcription, DNA-templated
protein-containing complex assembly
extracellular space
cellular nitrogen compound biosynthetic process
positive regulation of nucleic acid-templated transcription