EXOC5

Entrez Summary: N/A
UniProt Summary: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 6/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	2/21
liver	0/20
lung	1/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	2/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Ral GTPase binding
exocyst
establishment of planar polarity
establishment of tissue polarity
epithelial cell apoptotic process
morphogenesis of a polarized epithelium
non-motile cilium assembly
Golgi to plasma membrane transport
vesicle docking
vesicle-mediated transport to the plasma membrane
post-Golgi vesicle-mediated transport
protein N-terminus binding
midbody
organelle localization by membrane tethering
membrane docking
protein localization to plasma membrane
protein localization to cell periphery
cilium assembly
cilium organization
Golgi vesicle transport
morphogenesis of an epithelium
plasma membrane bounded cell projection assembly
cell projection assembly
protein localization to membrane
tissue morphogenesis
organelle localization
organelle assembly
exocytosis
apoptotic process
secretion by cell
export from cell
programmed cell death
cell death
epithelium development
plasma membrane bounded cell projection organization
secretion
cell projection organization
protein transport
peptide transport
amide transport