FAM19A3

Entrez Summary: N/A
UniProt Summary: Plays a role in the regulation of microglia polarization. {ECO:0000250|UniProtKB:Q7TPG6}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of microglial cell activation
positive regulation of microglial cell activation
negative regulation of neuroinflammatory response
positive regulation of neuroinflammatory response
negative regulation of macrophage activation
regulation of microglial cell activation
positive regulation of macrophage activation
regulation of neuroinflammatory response
receptor ligand activity
regulation of macrophage activation
negative regulation of inflammatory response
positive regulation of inflammatory response
negative regulation of leukocyte activation
negative regulation of cell activation
negative regulation of defense response
regulation of inflammatory response
negative regulation of response to external stimulus
positive regulation of leukocyte activation
positive regulation of cell activation
negative regulation of immune system process
positive regulation of defense response
positive regulation of response to external stimulus
regulation of leukocyte activation
regulation of cell activation
regulation of defense response
regulation of response to external stimulus
positive regulation of immune system process
regulation of response to stress
extracellular space
negative regulation of response to stimulus
regulation of immune system process