FMO1

Entrez Summary: N/A
UniProt Summary: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pyr redox 2
FMO-like

NADPH oxidation
N,N-dimethylaniline monooxygenase activity
toxin metabolic process
NADP metabolic process
monooxygenase activity
NADP binding
secondary metabolic process
flavin adenine dinucleotide binding
response to osmotic stress
xenobiotic metabolic process
cellular response to xenobiotic stimulus
response to xenobiotic stimulus
endoplasmic reticulum lumen
response to lipopolysaccharide
response to molecule of bacterial origin
drug metabolic process
response to bacterium
response to lipid
endoplasmic reticulum membrane
oxidation-reduction process
organic acid metabolic process
response to abiotic stimulus
response to other organism
response to external biotic stimulus
response to biotic stimulus
response to oxygen-containing compound
small molecule metabolic process