FOXD2

Entrez Summary: N/A
UniProt Summary: Probable transcription factor involved in embryogenesis and somatogenesis. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Epigallocatechin gallate 20μM R05 exp230	-2.15
Arsenic trioxide 60μM R08 exp449	-1.81
TRAIL 50ng/ml R00 exp36	-1.8
2-Methoxyestradiol 0.55μM R07 exp310	1.71
Vincristine 0.0005μM R04 exp190	1.71
Cytochalasin-B 5μM R07 exp349	1.75

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
positive regulation of transcription by RNA polymerase II
positive regulation of transcription, DNA-templated
DNA-binding transcription factor activity, RNA polymerase II-specific
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
positive regulation of RNA metabolic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process