FOXF2

Entrez Summary: FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008].
UniProt Summary: Probable transcription activator for a number of lung- specific genes.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Dihydrosphingosine 8μM R08 exp476	-1.9
FTY720 3μM R08 exp483	1.87

establishment of planar polarity of embryonic epithelium
regulation of protein polyubiquitination
establishment of planar polarity
establishment of tissue polarity
embryonic camera-type eye morphogenesis
embryonic eye morphogenesis
embryonic digestive tract development
embryonic camera-type eye development
morphogenesis of a polarized epithelium
genitalia development
epithelial to mesenchymal transition
roof of mouth development
camera-type eye morphogenesis
regulation of proteasomal ubiquitin-dependent protein catabolic process
digestive tract development
digestive system development
eye morphogenesis
regulation of ubiquitin-dependent protein catabolic process
mesenchymal cell differentiation
regulation of proteasomal protein catabolic process
regulation of protein ubiquitination
transcription factor complex
regulation of proteolysis involved in cellular protein catabolic process
mesenchyme development
regulation of protein modification by small protein conjugation or removal
regulation of cellular protein catabolic process
sensory organ morphogenesis
sex differentiation
embryonic organ morphogenesis
RNA polymerase II regulatory region sequence-specific DNA binding
camera-type eye development
transcription factor binding
extracellular matrix organization
eye development
visual system development
sensory system development
regulation of protein catabolic process
extracellular structure organization
sequence-specific DNA binding
reproductive structure development