GABRG1
Gene Information
- Official Symbol: GABRG1
- Official Name: gamma-aminobutyric acid type A receptor subunit gamma1
- Aliases and Previous Symbols: N/A
- Entrez ID: 2565
- UniProt: Q8N1C3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4. [provided by RefSeq, Jul 2008].
- UniProt Summary: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16518
- Expression level (log2 read counts): -4.27