GAL3ST3

Entrez Summary: N/A
UniProt Summary: Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha- 1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha- 1,4)GlcNAc. {ECO:0000269|PubMed:11323440, ECO:0000269|PubMed:11356829}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
galactosylceramide sulfotransferase activity
3-phosphoadenosine 5-phosphosulfate binding
poly-N-acetyllactosamine metabolic process
oligosaccharide metabolic process
glycolipid biosynthetic process
proteoglycan biosynthetic process
cellular polysaccharide metabolic process
polysaccharide metabolic process
Golgi cisterna membrane
proteoglycan metabolic process
glycolipid metabolic process
liposaccharide metabolic process
membrane lipid biosynthetic process
aminoglycan metabolic process
cellular carbohydrate metabolic process
carbohydrate binding
monosaccharide metabolic process
membrane lipid metabolic process
glycoprotein biosynthetic process
sulfur compound metabolic process
glycoprotein metabolic process
carbohydrate metabolic process
lipid biosynthetic process
carbohydrate derivative biosynthetic process
cellular lipid metabolic process
carbohydrate derivative metabolic process
lipid metabolic process
organonitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
small molecule metabolic process
macromolecule biosynthetic process