GJA3
Gene Information
- Official Symbol: GJA3
- Official Name: gap junction protein alpha 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 2700
- UniProt: Q9Y6H8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010].
- UniProt Summary: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7193
- Expression level (log2 read counts): 3.46