GOLGA7

Entrez Summary: N/A
UniProt Summary: May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. {ECO:0000269|PubMed:14522980, ECO:0000269|PubMed:16000296}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 3/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	1/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	1/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	1/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

palmitoyltransferase complex
intrinsic component of Golgi membrane
peptidyl-L-cysteine S-palmitoylation
peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
protein-cysteine S-palmitoyltransferase activity
Golgi to plasma membrane protein transport
protein palmitoylation
Golgi stack
peptidyl-cysteine modification
establishment of protein localization to plasma membrane
tertiary granule lumen
Golgi to plasma membrane transport
protein lipidation
lipoprotein biosynthetic process
vesicle-mediated transport to the plasma membrane
post-Golgi vesicle-mediated transport
lipoprotein metabolic process
protein targeting to membrane
protein stabilization
protein localization to plasma membrane
protein acylation
protein localization to cell periphery
establishment of protein localization to membrane
regulation of protein stability
protein targeting
Golgi vesicle transport
protein localization to membrane
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
leukocyte activation involved in immune response
cell activation involved in immune response
regulated exocytosis
leukocyte mediated immunity