GPC2

Entrez Summary: N/A
UniProt Summary: Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

anchored component of plasma membrane
glycosaminoglycan catabolic process
aminoglycan catabolic process
smoothened signaling pathway
lysosomal lumen
Golgi lumen
glycosaminoglycan biosynthetic process
retinoid metabolic process
aminoglycan biosynthetic process
diterpenoid metabolic process
terpenoid metabolic process
isoprenoid metabolic process
glycosaminoglycan metabolic process
aminoglycan metabolic process
regulation of protein localization to membrane
carbohydrate derivative catabolic process
synapse
positive regulation of neuron projection development
collagen-containing extracellular matrix
positive regulation of neuron differentiation
positive regulation of cell projection organization
positive regulation of neurogenesis
regulation of neuron projection development
positive regulation of nervous system development
regulation of cellular protein localization
positive regulation of cell development
cell surface
carbohydrate derivative biosynthetic process
regulation of neuron differentiation
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
regulation of cellular localization
regulation of nervous system development
regulation of cell development
cellular lipid metabolic process
cell migration
positive regulation of cell differentiation
endoplasmic reticulum
neuron differentiation