IL17D

Entrez Summary: N/A
UniProt Summary: Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells. {ECO:0000269|PubMed:12097364}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of granulocyte macrophage colony-stimulating factor production
regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of cytokine production involved in inflammatory response
receptor ligand activity
regulation of cytokine production involved in inflammatory response
positive regulation of interleukin-8 production
regulation of interleukin-8 production
positive regulation of interleukin-6 production
negative regulation of hemopoiesis
positive regulation of inflammatory response
regulation of interleukin-6 production
cytokine activity
regulation of inflammatory response
negative regulation of immune system process
positive regulation of cytokine production
regulation of hemopoiesis
positive regulation of defense response
inflammatory response
positive regulation of response to external stimulus
regulation of cytokine production
regulation of defense response
protein homodimerization activity
negative regulation of developmental process
regulation of response to external stimulus
negative regulation of multicellular organismal process
defense response
regulation of response to stress
extracellular space
regulation of immune system process
positive regulation of multicellular organismal process