WNT3A 44ng/ml R08 exp537
Mechanism of Action
Ligand for Frizzled receptor complex, stabilizes ‘_-catenin, induces TCS/LEF-dependent transcription
- Class / Subclass 1: Signal Transduction / GPCR Agonist
Technical Notes
Compound References
- PubChem Name: N/A
- Synonyms: MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt3a; Wnt-3a; MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt3a; Wnt-3a
- CAS #: N/A
- PubChem CID: N/A
- IUPAC: N/A
- INCHI Name: N/A
- INCHI Key: N/A
- Molecular Weight: 37.4kDa
- Canonical SMILES: N/A
- Isomeric SMILES: N/A
- Molecular Formula: MSYPIWWSLA VGPQYSSLGS QPILCASIPG LVPKQLRFCR NYVEIMPSVA EGIKIGIQEC QHQFRGRRWN CTTVHDSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGTAAICG CSSRHQGSPG KGWKWGGCSE DIEFGGMVSR EFADARENRP DARSAMNRHN NEAGRQAIAS HMHLKCKCHG LSGSCEVKTC WWSQPDFRAI GDFLKDKYDS ASEMVVEKHR ESRGWVETLR PRYTYFKVPT ERDLVYYEAS PNFCEPNPET GSFGTRDRTC NVSSHGIDGC DLLCCGRGHN ARAERRREKC RCVFHWCCYV SCQECTRVYD VHTCK
Compound Supplier
- Supplier Name: R&D system
- Catalog #: PSM5036
- Lot #: RSK8018031
Compound Characterization
Characterization data not available.
Dose Response Curve
- Platform ID: Wnt_3a
- Min: -15.7852; Max: 40.2171
| IC | Concentration (µM) |
|---|---|
| IC10 | N/A |
| IC20 | N/A |
| IC30 | N/A |
| IC40 | N/A |
| IC50 | N/A |
| IC60 | N/A |
| IC70 | N/A |
| IC80 | N/A |
| IC90 | N/A |
Screen Summary
- Round: 08
- Dose: 44ng/mL
- Days of incubation: 8
- Doublings: 7.2
- Numbers of reads: 15772202
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 0/0 | Scores |
WNT3A 44ng/ml R08 exp537
Bisphenol F 50μM R08 exp457 vs WNT3A 44ng/ml R08 exp537
Metformin 40μM R03 exp132 vs WNT3A 44ng/ml R08 exp537
