FRY

Gene Information
  • Official Symbol: FRY
  • Official Name: FRY microtubule binding protein
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 10129
  • UniProt: Q5TBA9
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation. {ECO:0000269|PubMed:22753416}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 16290
  • Expression level (log2 read counts): 2.33

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1