JAM2

Entrez Summary: N/A
UniProt Summary: May play a role in the processes of lymphocyte homing to secondary lymphoid organs.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cytochalasin-B 5μM R07 exp349	-2.1
Lead acetate 2000μM R08 exp498 no dilution day6	-1.9
Tozasertib 0.1μM R07 exp414	-1.83
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	-1.72
2-Deoxy-D-glucose 800μM R05 exp214	1.73

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

bicellular tight junction
negative regulation of cell adhesion
extracellular matrix organization
leukocyte migration
extracellular structure organization
protein heterodimerization activity
cell-cell adhesion
regulation of cell adhesion
cell adhesion
biological adhesion
cell migration
cell motility
localization of cell
locomotion
integral component of plasma membrane
movement of cell or subcellular component