KCNS1

Official Symbol: KCNS1
Official Name: potassium voltage-gated channel modifier subfamily S member 1
Aliases and Previous Symbols: N/A
Entrez ID: 3787
UniProt: Q96KK3
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2 (PubMed:10484328). {ECO:0000269|PubMed:10484328}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of delayed rectifier potassium channel activity
delayed rectifier potassium channel activity
potassium channel regulator activity
regulation of potassium ion transmembrane transporter activity
voltage-gated potassium channel activity
regulation of potassium ion transmembrane transport
voltage-gated potassium channel complex
regulation of potassium ion transport
potassium ion transmembrane transport
potassium ion transport
regulation of cation channel activity
regulation of ion transmembrane transporter activity
regulation of transmembrane transporter activity
regulation of transporter activity
regulation of cation transmembrane transport
protein homooligomerization
regulation of metal ion transport
monovalent inorganic cation transport
regulation of ion transmembrane transport
protein complex oligomerization
inorganic cation transmembrane transport
regulation of transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
perinuclear region of cytoplasm
regulation of ion transport
cation transport
ion transmembrane transport
transmembrane transport
ion transport
protein-containing complex assembly
protein-containing complex subunit organization
regulation of transport