KCTD20

Entrez Summary: N/A
UniProt Summary: Promotes the phosphorylation of AKT family members. {ECO:0000250|UniProtKB:Q8CDD8}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
JQ1 0.01μM R03 exp130	-1.8
UM131593 0.1μM R01 exp58	1.7
CI-1040 9.5μM R08 exp472	1.71
CVT-10216 0.1μM R06 exp278	1.8
Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53	1.96

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of phosphorylation
positive regulation of phosphate metabolic process
positive regulation of phosphorus metabolic process
regulation of phosphorylation
regulation of phosphate metabolic process
regulation of phosphorus metabolic process