KIF1B

Entrez Summary: This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

response to rotenone
anterograde neuronal dense core vesicle transport
retrograde neuronal dense core vesicle transport
dense core granule localization
dense core granule cytoskeletal transport
dense core granule transport
neuron-neuron synaptic transmission
secretory granule localization
response to insecticide
retrograde axonal transport
establishment of mitochondrion localization, microtubule-mediated
mitochondrion transport along microtubule
establishment of mitochondrion localization
ATP-dependent microtubule motor activity, plus-end-directed
microtubule associated complex
neuromuscular synaptic transmission
kinesin binding
anterograde axonal transport
vesicle transport along microtubule
lysosome localization
mitochondrion localization
vesicle cytoskeletal trafficking
cellular response to nerve growth factor stimulus
response to nerve growth factor
kinesin complex
axonal transport
axon cytoplasm
scaffold protein binding
axo-dendritic transport
microtubule motor activity
organelle transport along microtubule
kinase binding
response to antineoplastic agent
cytoplasmic vesicle membrane
cytosolic transport
transport along microtubule
establishment of vesicle localization
cytoskeleton-dependent intracellular transport
microtubule-based transport
vesicle localization