LAMB4

Entrez Summary: N/A
UniProt Summary: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Laminin EGF
Laminin N

laminin complex
basement membrane assembly
basement membrane organization
substrate adhesion-dependent cell spreading
extracellular matrix structural constituent
cell-substrate adhesion
extracellular matrix organization
extracellular structure organization
cell morphogenesis involved in differentiation
cell morphogenesis
cellular component morphogenesis
cell adhesion
biological adhesion
animal organ morphogenesis
cell migration
cell motility
localization of cell
locomotion
movement of cell or subcellular component
cell development
tissue development