LCE2D

Entrez Summary: N/A
UniProt Summary: Precursors of the cornified envelope of the stratum corneum.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Thimerosal 0.85μM R08 exp529	-1.87
Bisphenol S 100μM R08 exp458	-1.72
42°C R08 exp539	1.78
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	2.01

peptide cross-linking
cornified envelope
structural molecule activity
keratinization
keratinocyte differentiation
epidermal cell differentiation
skin development
epidermis development
epithelial cell differentiation
epithelium development
tissue development