LGALS16

Entrez Summary: N/A
UniProt Summary: Binds lactose with high affinity. Strong inducer of T- cell apoptosis. {ECO:0000269|PubMed:19497882}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

lactose binding
positive regulation of T cell apoptotic process
positive regulation of lymphocyte apoptotic process
positive regulation of leukocyte apoptotic process
regulation of T cell apoptotic process
regulation of lymphocyte apoptotic process
regulation of leukocyte apoptotic process
cellular component
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
apoptotic process
programmed cell death
cell death
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death