LRFN1

Official Symbol: LRFN1
Official Name: leucine rich repeat and fibronectin type III domain containing 1
Aliases and Previous Symbols: N/A
Entrez ID: 57622
UniProt: Q9P244
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of postsynaptic density assembly
regulation of postsynaptic specialization assembly
regulation of postsynapse assembly
regulation of excitatory synapse assembly
regulation of postsynaptic density organization
integral component of postsynaptic density membrane
regulation of postsynapse organization
regulation of synapse assembly
regulation of synapse organization
regulation of organelle assembly
regulation of synapse structure or activity
cell junction
cell surface
regulation of nervous system development
regulation of cellular component biogenesis
regulation of organelle organization