MAB21L1

Gene Information
  • Official Symbol: MAB21L1
  • Official Name: mab-21 like 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 4081
  • UniProt: Q13394
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene is similar to the MAB-21 cell fate-determining gene found in C. elegans. It may be involved in eye and cerebellum development, and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders. [provided by RefSeq, Oct 2008].
  • UniProt Summary: Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity). It is unclear whether it displays nucleotidyltransferase activity in vivo (PubMed:27271801). Binds single-stranded RNA (ssRNA) (PubMed:27271801). {ECO:0000250|UniProtKB:O70299, ECO:0000269|PubMed:27271801}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8252
  • Expression level (log2 read counts): -6.6

Expression Distribution

  • Last modified: 2026/01/07 22:36
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