MALRD1

Entrez Summary: N/A
UniProt Summary: Enhances production and/or transport of FGF19 and thus has a role in regulation of bile acid synthesis. {ECO:0000269|PubMed:23747249}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

Screen	Score
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	-1.76
MK-1775 0.32μM R02 exp75	2.03

Ldl recept a
MAM

negative regulation of bile acid biosynthetic process
negative regulation of bile acid metabolic process
regulation of bile acid biosynthetic process
regulation of bile acid metabolic process
negative regulation of steroid biosynthetic process
negative regulation of steroid metabolic process
negative regulation of lipid biosynthetic process
cholesterol homeostasis
sterol homeostasis
negative regulation of lipid metabolic process
regulation of steroid biosynthetic process
negative regulation of small molecule metabolic process
regulation of steroid metabolic process
lipid homeostasis
cytoplasmic vesicle membrane
regulation of cellular ketone metabolic process
regulation of lipid biosynthetic process
regulation of lipid metabolic process
regulation of small molecule metabolic process
Golgi apparatus
chemical homeostasis
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
homeostatic process