MATN3

Gene Information
Function Summary
  • Entrez Summary: This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7867
  • Expression level (log2 read counts): -3.59

Expression Distribution

  • Last modified: 2026/01/07 22:36
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