MMP28

Entrez Summary: N/A
UniProt Summary: Can degrade casein. Could play a role in tissues homeostasis and repair.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	1/5

Expression Distribution

negative regulation of macrophage chemotaxis
negative regulation of macrophage migration
negative regulation of leukocyte chemotaxis
regulation of macrophage chemotaxis
regulation of macrophage migration
collagen catabolic process
negative regulation of leukocyte migration
negative regulation of chemotaxis
collagen metabolic process
metalloendopeptidase activity
regulation of leukocyte chemotaxis
regulation of leukocyte migration
regulation of chemotaxis
extracellular matrix
negative regulation of cell migration
negative regulation of cell motility
negative regulation of cellular component movement
negative regulation of locomotion
extracellular matrix organization
collagen-containing extracellular matrix
negative regulation of response to external stimulus
extracellular structure organization
negative regulation of immune system process
zinc ion binding
regulation of cell migration
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
regulation of response to external stimulus
proteolysis
extracellular space
negative regulation of response to stimulus
regulation of immune system process