MOB2

Entrez Summary: N/A
UniProt Summary: Stimulates the autophosphorylation and kinase activity of STK38 and STK38L. {ECO:0000269|PubMed:15067004}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

neuron projection terminus
positive regulation of neuron projection development
positive regulation of neuron differentiation
positive regulation of cell projection organization
positive regulation of neurogenesis
actin cytoskeleton organization
regulation of neuron projection development
positive regulation of nervous system development
positive regulation of cell development
actin filament-based process
regulation of neuron differentiation
regulation of plasma membrane bounded cell projection organization
perinuclear region of cytoplasm
regulation of cell projection organization
regulation of neurogenesis
nucleolus
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation
positive regulation of protein phosphorylation
positive regulation of phosphorylation
cytoskeleton organization
positive regulation of phosphorus metabolic process
positive regulation of phosphate metabolic process
positive regulation of cellular component organization
positive regulation of protein modification process
positive regulation of developmental process
regulation of protein phosphorylation
generation of neurons
regulation of phosphorylation
positive regulation of cellular protein metabolic process
neurogenesis
positive regulation of protein metabolic process
positive regulation of multicellular organismal process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of cell differentiation
regulation of protein modification process