MYCBPAP

Entrez Summary: N/A
UniProt Summary: May play a role in spermatogenesis. May be involved in synaptic processes (By similarity). {ECO:0000250|UniProtKB:Q69CM7, ECO:0000269|PubMed:12151104}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	-2.74
Deferoxamine 11μM R07 exp350	-2.15
THZ531 0.11 to 0.175μM on day4 R07 exp413	-1.89
Losmapimod 1μM R07 exp376	-1.7

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
synaptic signaling
spermatogenesis
male gamete generation
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
cell-cell signaling
reproductive process
reproduction
membrane