MYO1A
Gene Information
- Official Symbol: MYO1A
- Official Name: myosin IA
- Aliases and Previous Symbols: N/A
- Entrez ID: 4640
- UniProt: Q9UBC5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011].
- UniProt Summary: Involved in directing the movement of organelles along actin filaments. {ECO:0000305}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3339
- Expression level (log2 read counts): -1.47