NMUR1

Entrez Summary: N/A
UniProt Summary: Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250, ECO:0000269|PubMed:10899166}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

7tm 1
7TM GPCR Srsx

neuromedin U binding
neuromedin U receptor activity
neuropeptide receptor activity
inositol phosphate-mediated signaling
activation of phospholipase C activity
positive regulation of phospholipase C activity
regulation of phospholipase C activity
smooth muscle contraction
positive regulation of phospholipase activity
regulation of phospholipase activity
positive regulation of lipase activity
phospholipase C-activating G protein-coupled receptor signaling pathway
regulation of lipase activity
chloride transport
neuropeptide signaling pathway
calcium-mediated signaling
inorganic anion transport
calcium ion transport
muscle contraction
divalent metal ion transport
muscle system process
divalent inorganic cation transport
second-messenger-mediated signaling
anion transport
metal ion transport
G protein-coupled receptor activity
positive regulation of hydrolase activity
cation transport
regulation of hydrolase activity
G protein-coupled receptor signaling pathway
ion transport
integral component of plasma membrane
positive regulation of catalytic activity
intracellular signal transduction
positive regulation of molecular function
system process