NOVA1

Entrez Summary: N/A
UniProt Summary: May regulate RNA splicing or metabolism in a specific subset of developing neurons.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
35°C R06 exp302	1.82
Cincreasin 100μM R08 exp473	1.82

negative regulation of cold-induced thermogenesis
regulation of cold-induced thermogenesis
mRNA binding
locomotory behavior
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
RNA splicing
chemical synaptic transmission
anterograde trans-synaptic signaling
trans-synaptic signaling
synaptic signaling
mRNA processing
behavior
intracellular membrane-bounded organelle
mRNA metabolic process
nucleolus
RNA processing
cell-cell signaling
negative regulation of multicellular organismal process
RNA binding
RNA metabolic process
gene expression